Gnome. Mostly vanilla except for some extended tiling for when I need it. Also sped up animations.
I bind Activities to an extra mouse button. But I'm also comfortable without that.
I've used a lot of stuff over the years. Started with the kde 3 series. I just don't really want to do a lot of fiddling anymore, and find the default Gnome workflow to be a really good fit for me.
10+ years ago there was something called Basket Note Pads that had the same blank canvas style note taking that onenote has now.
My heart broke in two when the project died because the metaphor wasn't popular at the time. It'd be so well positioned if it had stayed in development until today.