this post was submitted on 17 Aug 2023
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It uncovered eight WHO panelists involved with assessing safe levels of aspartame consumption who are beverage industry consultants who currently or previously worked with the alleged Coke front group, International Life Sciences Institute (Ilsi).

Their involvement in developing intake guidelines represents “an obvious conflict of interest”, said Gary Ruskin, US Right-To-Know’s executive director. “Because of this conflict of interest, [the daily intake] conclusions about aspartame are not credible, and the public should not rely on them,” he added.

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[–] Silverseren@kbin.social 3 points 1 year ago (2 children)

I'm sorry that people actually knowing biochemistry is such a problem for you.

Question: How can a dipeptide of two common amino acids, phenylalanine and aspartic acid, that dissociate in your stomach cause negative health impacts?

[–] Dr_Cog@mander.xyz 4 points 1 year ago (1 children)

Just as easily as a molecule with two carbons, one nitrogen, one oxygen, and a hydrogen. Just because chemicals are simple doesn't mean they are safe.

[–] Silverseren@kbin.social 2 points 1 year ago (2 children)

That's not really an answer. Any impact that aspartame would have, the same impact would occur from phenylalanine and aspartic acid consumption. And considering we both have no evidence for such impacts and both amino acids are critical for this whole being alive thing, that means there is no biochemical basis for claims of harm in the first place.

[–] Dr_Cog@mander.xyz 3 points 1 year ago

My point is that just because a compound is simple or easily understood doesn't mean it is safe. What if excess phenylalanine is toxic? It's not completely outside of the realm of possibility.

For the record, I agree with you that it is unlikely that aspartame is toxic and the only studies that show this use non-human analogues. It is, however, important to play devil's advocate in scientific settings.

[–] Poopmeister@lemm.ee 2 points 1 year ago

I read some study that aspartame changed the gut flora. Sugar probably does the same thing though. But sometimes there's interactions that science forget to study

[–] Amir@lemmy.ml 2 points 1 year ago* (last edited 1 year ago) (1 children)

Everything has a negative health impact, literally even water does. The question is always about cumulative and spontaneous dosage. At what point does it become bad for you.

One common explanation I've seen for aspartame is that it makes your body think you're drinking sugar while no sugar is being absorbed. This is then potentially harmful for those with a predisposition for diabetes.

[–] Silverseren@kbin.social 1 points 1 year ago (1 children)

That is a known effect, yes. And an understandable one that occurs just because of the sweet receptor response. But that has nothing to do with the effects being claimed by others about it.

[–] Amir@lemmy.ml 1 points 1 year ago (1 children)

It's possible that the increased risk of diabetes snowballs into an increased risk of cancer from diabetes' secondary conditions. Making claims about "these amino acids are harmless so the substance is harmless" disregards the possible chains of events that could actually cause more conditions.

[–] Silverseren@kbin.social 1 points 1 year ago

That is something that can be researched and would apply to anything that tastes sweet, of course, if true. But that's still not the things being claimed by people about the impacts aspartame is having on them.

Essentially, they're making claims akin to the MSG conspiracies, with the same lack of evidence for anything. Including with placebo studies showing the people claiming these effects also claiming it when they think they're consuming the substance, but they aren't.