Technology

It’s its own rant

I sympathise with the state of diabetic sensor apps, but can I just say that it makes me so happy when people understand and use correct grammar.

I you make your own, there is no risk for blindness. Blindness comes from methanol, not ethanol. If you use a yeast based process to produce the alcohol and then distill it, there is no way to accidentally produce methanol in that process. The cases where people get blind or die from moonshine stems from when the feds replaced moonshine with methanol to be able to make that claim and disrupt the business of organized crime during the prohibition. There are still cases now and then where people try to make drinkable alcohol from some industrial base and don't know how to.

TLDR: Don't buy, make.

And that’s different from the commercial pharmaceutical industry how?

As opposed to dying from the disease you already have because the traditional pharmaceutical industry makes the drugs you need out of your price range?

It won't be a life long ailment for long if you're going to die from a lack of care soon anyways.

404 Media is doing excellent work; if you like this kind of thing you might want to sign up for their newsletter.

My first thought when I saw the headline was "Can it help me pull this tooth without it hurting so badly?"

True. A lot of drugs you can perform tests on. But there is an inherent risk. I don't think making medicine at home is going to be many people's first choice. I think the people most likely to pursue this are those for whom obtaining medication other ways is not possible. When the government makes it impossible for someone to obtain health care, either due to literally making it illegal or by allowing it to become completely unaffordable for working class people, then they have to resort to other options.

With patience and diligent work it is possible to make many medications with (by comparison) significantly cheaper resources. And if someone were to do this, presumably, there are others who also have similar needs for the medications being produced. Which is how community medicine networks are formed. DIY Hormone replacement medications for trans people living in places where it's illegal for them to access medication, or otherwise extremely difficult often access medicines made through networks like that.

This isn't really a new thing, but the ease of access to documentation on how to do it certainly is new.

Pirating movies and games can't kill you

Home brewing seizure medication can

The all new sudafeb....like Sudafed but with a D at the end because they're chemically the same just with a D at the end.

You've gone to a malicious website. Now you've died.

See, the risks of surfing the web incorrectly are slightly different than the risks of creating medicine incorrectly.

They could do that, but the drugs are still much too expensive comparatively, and it doesn't include many drugs, especially the ones that are the most absurdly priced.

For instance, after looking through various articles on him and scraping together some of the data, out of the medications referenced as being some that he's made:

Misoprostol (Abortion Medication) - $14.90 on CPG - $0.89 via MicroLab

Sovaldi (Cures Hepatitis C) - Not available on CPG (normally $84,000) - $70 via MicroLab

Kalydeco (Treats Cystic Fibrosis) - Not available on CPG (Normally ~$500/day) - $10/day via MicroLab

Daraprim (Treats Parasitic Diseases & Some AIDS Patients) - $2443/30 pills on CPG - $80/30 Pills via MicroLab

Epinephrine (Treats Allergic Reactions, AKA epipen) - Not available on CPG (Normally $650-$750) - Initially $30 via MicroLab ($3/reload after)

The pharmaceutical industry is so screwed up, and these prices only show it more clearly.

They don't have everything and especially rare mega expensive stuff that's not widely generic options

Obviously the people who would benefit most from this technology would prefer a doctor and pharmacy to be involved as well. The point is that personal preference doesn't really mean much when the preferred option is inaccessible and the alternative is death or a dramatically reduced quality of life. You do the best with what you have.

Well that's the coolest part about this, everything is based on the existing research.

The drugs they're making are the exact same chemical compounds formulated by the drug companies, and contrary to popular belief, the compounds can actually be relatively simple, it's the process of finding which compound that takes the most money from R&D.

So if you have 2-3 very standard chemicals, with well known reactions and outcomes, and you have the exact blueprint of what the final result should look like, and you can chemically test it afterward to see if it combined as expected, then anyone who has enough reason to use this instead of traditional means (i.e. being priced out of lifesaving medication completely) can be reasonably confident it will work.

And it's only made more inspiring by the fact that he has his own personal history with the pharmaceutical industry that didn't work for him.

I found another article on him and the collective, and there's this honestly saddening quote:

“A toast to the dead, for children with cancer and AIDS,” Laufer said, raising a glass of bourbon and quoting the hip hop artist Felipe Andres Coronel, better known as Immortal Technique. “A cure exists, and you probably could have been saved.”

It's even posted up on their page for the MicroLab right at the top.

This could be very good for people with orphan diseases(diseases that are rare enough that they aren't profitable for private companies to research)

Also, having an orphan disease often results in insurance companies denying coverage for everything because they don't have a policy written up for that specific disease.... so there's no script for the workers to follow. Then your doctor has to argue with them, which can take weeks, in the meantime you have no medication.

Yeah, I'm not mad or anything. I wish I could've cooked up my own meds when insurance denied me life giving meds because they'd never heard my disorder.

that’s not the full story though. according to the NIH, the US government spent over 30 billion dollars on the covid vaccines.

and this is not unique to the covid vaccine. here’s a source with two particularly damning quotes:

“Since the 1930s, the National Institutes of Health has invested close to $900 billion in the basic and applied research that formed both the pharmaceutical and biotechnology sectors.”

and

A 2018 study on the National Institute of Health’s (NIH) financial contributions to new drug approvals found that the agency “contributed to published research associated with every one of the 210 new drugs approved by the Food and Drug Administration from 2010–2016.” More than $100 billion in NIH funding went toward research that contributed directly or indirectly to the 210 drugs approved during that six-year period.

If it was the best healthcare in the world, we’d have the best outcomes and we don’t even have that for rich people. We have a (non-metric) shit ton of world class research universities and highly respected agencies like the FDA and NHS but Elon Musk, the richest man in the world, can’t even get the mental health services he obviously needs.

I’d obviously rather go to an American hospital than a hospital in most of the world but spending a lot to cover up a shitty system isn’t as good as a functioning system.